R Tutorial - Introducing biology of genomic datasets

The Science of Organisms and Genomes: A Comprehensive Guide to Understanding Life at its Core

Organisms are complex structures that consist of various interconnected elements, which work together to integrate their overall functioning. The diversity of organisms is vast, ranging from unicellular to multicellular, with a nucleus and without it, different membranes, systems, and life cycles. In recent times, scientists have made significant progress in studying organisms in detail by sequencing genomes and dissecting their elements to find interesting functions.

At the heart of every organism lies its genome, which is the complete genetic material that makes up what an organism is and dictates its responses to external influences. A genome is essentially a blueprint of life, consisting of long sequences of DNA based on a four-letter alphabet (T, A, G, and C). The reading information in a genome uses this DNA alphabet, making it possible for us to locate and describe specific locations within the genome.

To understand the complexities of genomes, we subdivide them into various components. Each chromosome is like a book with ordered genetic sequences that contain specific instructions. Genes are like pages in a book containing recipes to make proteins. These genes can be categorized as either coding or non-coding, depending on their function. Coding genes are expressed through proteins responsible for specific functions, while non-coding genes do not produce proteins but still play important roles in the organism.

The process of creating proteins from DNA is a two-step process known as transcription and translation. Transcription involves converting DNA into RNA, which is then translated into protein. This process is essential for understanding how genes function and how they contribute to the overall functioning of an organism.

One of the most fascinating organisms that scientists have studied extensively is Saccharomyces cerevisiae, also known as baker's yeast or brewer's yeast. This single-cell microorganism has been found to be highly useful in fermentation, production, and bioremediation processes. The scientific name for this fungus was previously unknown, but it has now been identified as "Sakar mices Visia" due to its fast development rate, making it an ideal model organism for experiments.

The yeast genome is a valuable data set that provides insights into the genetic material of this fascinating microorganism. It is available in various packages and tools that can be used to learn about the genome, including the BS Genomics package. This package offers several functions that can help scientists understand the yeast genome better, such as determining the number of chromosomes, identifying chromosome names, and analyzing the length and composition of each chromosome.

One of the exciting features of the BS Genomics package is its ability to retrieve sections of a genome based on specific locations or parameters. For example, using the function "seqs" with the minimum argument, scientists can access all the sequences in the yeast genome. They can also specify additional parameters to select sequences from specific chromosomes or regions, such as chromosome M, using the function "CHR M". Furthermore, they can even specify the location of the sequences, such as starting at a certain position and selecting a specified number of base pairs.

Now it's your turn to explore the yeast genome using the functions from the BS Genomics package. With these tools, you can learn more about the genetic material that makes up this fascinating microorganism and gain insights into its functions and characteristics. The study of genomes and organisms is an ongoing endeavor that has revolutionized our understanding of life at its core.

"WEBVTTKind: captionsLanguage: enhi this is to introduce a bit of cell biology talking about organisms genomes and the yeast genome an organism is accomplice structure and interconnected elements integrate the overall functioning of the bear organisms diversity is in men's from unicellular to multicellular with a nucleus and without it different membranes and systems different life cycles and more in our time we study organisms in detail by sequencing genomes and dissecting its element to find interesting functions all organisms have a genome which makes up what they are and it dictates responses to external influences a genome is the complete genetic material of an organism store mostly in the chromosomes it is known as the blueprint of the living a genome is made of long sequences of DNA based on a four-letter alphabet T a G and C we are interested in locating and describing specific locations in a genome because this allowed us to learn about diversity evolution hereditary changes and more to understand this better we subdivide a genome the reading information in a genome uses the DNA alphabet think of a genome as a set of books and each book is a chromosome chromosome numbers on each genome are highly variable usually chromosomes come in pairs but multiple sets are very common to each chromosome has ordered genetic sequences think of chapters in a book to find specific genetic instructions we'll look at genes these are like the pages in a book containing a recipe to make proteins some genes will produce proteins but some want these are called coding and non-coding genes coding genes are expressed through proteins responsible for specific functions proteins come up following a two-step process DNA to RNA step known as transcription while the RNA to protein is step code translation as an example we are going to study the yeast genome a single-cell micro organism the fungus that people love is this useful fermentation and production of beer bread kefir kombucha and other foods as well as for bioremediation its scientific name is sekar mices Visia or as service' this is a very well study organism due to his fast development many experiments use it as a model the yeast genome is a data set available from you CSE we have picked this Hinnom because it has a small size in the following exercises you will find out more about this Tina for example you can call a specific gene invasion and assign it to an object as shown in the second line the BS genome package provide us with many genome data sets to get a list of the BS genome available data set is the function available that genomes then using common accessor functions you can learn about the genome for example the number of chromosomes using length the names of the chromosomes using names and the length of each chromosome by DNA base pair using SiC lengths specific genes all regions are interesting because of their functions you can retrieve sections of a genome with the function yet sick the minimum argument requires the bs genome the first example will give you all of the sequences in against genome then you can specify some other parameters to select sequences from chromosome m use CHR M next you can specify the locations of the sequences to distract using start and or with using and equals 10 selects the first 10 base pairs of each chromosome of the genome now it's your turn to explore the yeast genome using the functions from the bs genome padhi this is to introduce a bit of cell biology talking about organisms genomes and the yeast genome an organism is accomplice structure and interconnected elements integrate the overall functioning of the bear organisms diversity is in men's from unicellular to multicellular with a nucleus and without it different membranes and systems different life cycles and more in our time we study organisms in detail by sequencing genomes and dissecting its element to find interesting functions all organisms have a genome which makes up what they are and it dictates responses to external influences a genome is the complete genetic material of an organism store mostly in the chromosomes it is known as the blueprint of the living a genome is made of long sequences of DNA based on a four-letter alphabet T a G and C we are interested in locating and describing specific locations in a genome because this allowed us to learn about diversity evolution hereditary changes and more to understand this better we subdivide a genome the reading information in a genome uses the DNA alphabet think of a genome as a set of books and each book is a chromosome chromosome numbers on each genome are highly variable usually chromosomes come in pairs but multiple sets are very common to each chromosome has ordered genetic sequences think of chapters in a book to find specific genetic instructions we'll look at genes these are like the pages in a book containing a recipe to make proteins some genes will produce proteins but some want these are called coding and non-coding genes coding genes are expressed through proteins responsible for specific functions proteins come up following a two-step process DNA to RNA step known as transcription while the RNA to protein is step code translation as an example we are going to study the yeast genome a single-cell micro organism the fungus that people love is this useful fermentation and production of beer bread kefir kombucha and other foods as well as for bioremediation its scientific name is sekar mices Visia or as service' this is a very well study organism due to his fast development many experiments use it as a model the yeast genome is a data set available from you CSE we have picked this Hinnom because it has a small size in the following exercises you will find out more about this Tina for example you can call a specific gene invasion and assign it to an object as shown in the second line the BS genome package provide us with many genome data sets to get a list of the BS genome available data set is the function available that genomes then using common accessor functions you can learn about the genome for example the number of chromosomes using length the names of the chromosomes using names and the length of each chromosome by DNA base pair using SiC lengths specific genes all regions are interesting because of their functions you can retrieve sections of a genome with the function yet sick the minimum argument requires the bs genome the first example will give you all of the sequences in against genome then you can specify some other parameters to select sequences from chromosome m use CHR M next you can specify the locations of the sequences to distract using start and or with using and equals 10 selects the first 10 base pairs of each chromosome of the genome now it's your turn to explore the yeast genome using the functions from the bs genome pad\n"